Ventricular fibrillation during partial reperfusion following severe myocardial ischemia in the canine model.
作者： Takashi Ohkita , Yasuo Nagamoto , Masasuke Fujita , Masami Kuriyama , Akio Kuroiwa
DOI: 10.1016/0022-0736(90)90125-L
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摘要: Abstract The authors examined whether partial reperfusion protects against ventricular fibrillation (VF) following severe acute myocardial ischemia. Fifty-seven dogs were divided into two groups. In group A (n = 21), the left anterior descending coronary artery was occluded for 10 minutes, followed by full reperfusion. remaining 36 (group B), ischemia induced retrograde blood flow (RBF) minutes. Thereafter, these three subgroups: in B1 10), made a carotid-left bypass; B2 13), achieved collateral ischemic zone due to stopping RBF; B3 RBF continued an additional 5 During minute ischemia, at measured H2 gas-clearance method 12.3 ± 2.0 ml/min/100 g A, 3.4 0.9 B1, 4.7 0.6 B2, and (A vs p 3 21 ) 80% ( 8 69% 9 13
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