Are all the hypertensives made equal

摘要: Blood pressure lowering in hypertensive patients is of significant importance. The complex pathophysiology makes the therapeutic targets many, and extensive research has provided us with many antihypertensive drugs. However, data indicate that proportion controlled blood far from satisfying. This may partly be explained by a lack individualized treatment. Present guidelines for management hypertension emphasize thorough evaluation patient necessary before initiating Based on information about gender, age, ethnicity, family history, clinical examination concomitant diseases like diabetes mellitus, coronary heart disease, failure, cerebrovascular disease gout, physician able to provide best most need two three drugs control pressure. Thus, we methods predict responses various individual patients. Possibly, future treatments based upon genetic variants. Until now, several polymorphisms genes regulating have been located, these influence results are heterogeneous contradictory, yet not capable determining treatment properties. Coming years challenge further clarify potentially important aspects Meanwhile, physicians obligated individualize other means, examination.