Process for the depletion or removal of endotoxins

作者: Metin Colpan , Joachim Schorr , Peter Moritz

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摘要: A process for the depletion or removal of endotoxins from preparations containing active ingredients designated therapeutical use which are obtained natural sources by genetic engineering and/or biotechnology treatment with chromatographic material wherein said lysed, fractions optionally centrifuged, filtrated treated affinity methods; preincubated an aqueous salt solution and detergents, anion exchange then washed another solution, eluted exchanger, followed further purification in a per se known manner.

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