The Chemistry of Lactim Ethers. V. Reaction of Lactim Thioethers with β-Aminoesters

摘要: Reaction of a cyclic β-aminoester such as 2-ethoxycarbonylmethylpiperidine (5) with the lactim thioethers 1b and 1c gave 10-membered diamide (7) an 11-membered ring compound (9), respectively. On other hand, though acyclic β-aminoesters (6) reacted 1 to afford methyl 3-methylthiopropionate (11), N-alkyl 3-methylthiopropionamide (12), lactams (13), amidines (14), no was obtained.