Effect of glucomannan on obese patients: a clinical study.

摘要: An eight-week double-blind trial was conducted to test purified glucomannan fiber as a food supplement in 20 obese subjects. Glucomannan (from konjac root) or placebo given 1-g doses (two 500 mg capsules) with 8 oz water, 1 h prior each of three meals per d. Subjects were instructed not change their eating exercise patterns. Results showed significant mean weight loss (5.5 lbs) using over an period. Serum cholesterol and low-density lipoprotein significantly reduced (21.7 15.0 mg/dl respectively) the treated group. No adverse reactions reported.