QUANTITATIVE AND QUALITATIVE CHANGES IN THE "DARK" CELLS OF THE RENAL COLLECTING TUBULES IN RATS DEPRIVED OF WATER.

摘要: There is evidence that the renal collecting tubule involved in final concentration of urine, but fact its wall built up two different kinds cells has not hitherto been taken into account. The possible role one these, “dark” cell, investigated by quantitative and qualitative methods. Collecting tubules were isolated digestion collagenase from kidneys normal rats deprived water for 48 hr.; dark identified staining with Nitro BT method succinic dehydrogenase. number was counted; classified on a percentage basis three groups, containing less than 30, 30-50, more 50 respectively; cytological cytochemical observations also made. It found both changes occurred dehydrated rats. seems these secrete lumen. suggested may differ each other functionally. results are discussed relation to Ginetzynski's hypothesis ADH causes hyaluronidase be secreted tubule.