Management of Anti-EGFR-Targeting Monoclonal Antibody-Induced Hypomagnesemia

作者: R.L. Mani , M.F.W. Smith

DOI: 10.1159/000224441

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摘要: Targeting the epidermal growth factor receptor (EGFR) has proven to be of clinical benefit in management metastatic colorectal cancer (mCRC). While use small-molecule tyrosine kinase inhibitors this setting not shown any significant activity and been associated with increased gastrointestinal toxicity when combined chemotherapy, a different picture emerged EGFR-targeting monoclonal antibodies.

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