The hypolipidaemic activity of aqueous Erica multiflora flowers extract in Triton WR-1339 induced hyperlipidaemic rats: a comparison with fenofibrate.

摘要: Abstract In the present study, an aqueous extract from Erica multiflora L. (Ericaceae) flowers was evaluated for its hypocholesterolaemic and hypotriglyceridaemic activities using Triton WR-1339 induced hyperlipemic rats as experimental model. Hyperlipideamia developed by intraperitonial injection of (200 mg/kg body weight). The animals were divided into control (CG), hyperlipidaemic (HG), plus herb (HG + EmE) fenofibrate (HG + FF) treated groups. Intragastric administration (0.25 g/100 g weight) to caused a significant decrease on their plasma lipid levels (quantified enzymatic kits). At 7 h after treatment, total cholesterol, triglycerides LDL-cholesterol decreased 47%, 95% 67%, respectively, but change HDL-cholesterol level not significant. However, hypolipidaemic effect limited LDL-cholesterol, which lowered about 92% 41%, respectively. 24 h reduced cholesterol 68.5% 91%. significantly increased 80.5%. rats, only triglyceride concentrations 82%, while other parameters changed indicating that this may contain products lower might be beneficial in treatment hyperlipideamia.