HUMAN IMMUNODEFICIENCY VIRUS DETECTED IN BOWEL EPITHELIUM FROM PATIENTS WITH GASTROINTESTINAL SYMPTOMS
作者： JayA. Nelson , Catherine Reynolds-Kohler , William Margaretten , ClaytonA. Wiley , CharlesE. Reese
DOI: 10.1016/S0140-6736(88)90348-0
关键词:
摘要: Infectious human immunodeficiency virus (HIV) was recovered from two out of four bowel biopsy specimens acquired syndrome (AIDS) patients with chronic diarrhoea unknown aetiology. In-situ hybridisation rectum and duodenum other AIDS gastrointestinal complaints showed the presence HIV-infected cells in both base crypts lamina propria. The type(s) epithelial cell(s) infected could not be determined definitively. However, association in-situ labelling HIV RNA argentaffin staining strongly suggests that enterochromaffin derived neural crest tissue are among target cells. This evidence can directly infect raises possibility causes some disorders patients.
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