Cells Infected by Human Immunodeficiency Virus in Vivo
作者： Catherine Reynolds-Kohler , Clayton Wiley , Jay A. Nelson
DOI: 10.1007/978-1-4684-5976-0_3
关键词:
摘要: The identification of human immunodeficiency virus (HIV) as the etiologic agent AIDS has permitted characterization by in vitro culture analysis. ability to make HIV nucleic acid and antibody probes also allowed us determine involvement disease mechanisms vivo. Classically, is known have a preferential tropism for cells that express CD4 receptor1. These include T helper many monocyte-macrophage lineage1-4. In addition monocyte/macrophages, variety other cell types been shown support growth including B-cells, Langerhans cells, follicular dendritic glial colon5-9. order understand mechanism fo infection it important identify naturally infected with virus. following chapter describes are three distinct tissues. By utilizing situ hybridization immunocytochemistry techniques we analyzed brain, bowel placental tissue presence antigen. this applied these key possible transmission
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