Alterações comportamentais na Síndrome de Noonan: dados preliminares brasileiros
作者： Chong Ae Kim , María Cristina Triguero Veloz Teixeira , Érica Regina Mota , Débora Romero Bertola
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摘要: Different from other countries of Europe and North American, studies about the behavioral profile Noonan syndrome's patients are inexistent. The objective this study was to report profiles functions 10 participants (4 females 6 males), with mutations in PTPN11 gene. For assessment it used Inventory Behaviors Children Adolescents 18 years (CBCL/6-18) Auto-Evaluation for Adults 59 (ASR). main results point that Adaptive Functioning Scale all were normality range. In Syndrome adult range children clinical sub-scales anxious/depressed, somatic complaints aggressive behavior. DSM-Oriented Scale, 25% borderline range, respectively, Avoidant Personality Problems Antisocial Problems. About both scale Affective Anxiety This relatively homogenous sample, regarding gene, shows a normal profile, on average. However, individual show diverse internalizing externalizing disturbances.
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