Urinary NMP22 BladderChek test in the diagnosis of superficial bladder cancer.

摘要: Abstract Objective To study the diagnostic efficacy of NMP22 ® BladderChek test and to compare it cytology in detection bladder cancer. Methods We evaluated 106 voided urinary specimens patients with suspicion All urine samples were by test, cytology, sediment culture. The value was according correlation cystoscopic findings and, case tumour, histological findings. A negative result a pTaG1 tumour not considered false-negative this study. results compared cytology. Moreover, combination determined. Results In total, 29 had histologically proven transitional cell carcinoma bladder. detected 40% 15 pTa tumours 83.3% 6 pT1 tumours. Cytology 33.3% 66.6%. 1 CIS lesion group follow-up sensitivity specificity 57.1% (CI 28.8–82.3) 89.8% 79.2–96.2) for 42.9% 17.7–71.7) 93.2% 83.5–98.1) Conclusion has slightly higher without relevant loss specificity. Furthermore is an easy instant result. However, no extra adjunction test.