Multicentre experience with MGuard net protective stent in ST-elevation myocardial infarction: safety, feasibility, and impact on myocardial reperfusion.

摘要: Objective: To report, for the first time, angiographic and ECG results as well in-hospital 1-month clinical follow-up, after MGuard net protective stent (Inspire-MD, Tel-Aviv, Israel—MGS) implantation in consecutive, not randomized, STEMI patients undergoing primary or rescue PCI. Background: Distal embolization may decrease coronary myocardial reperfusion percutaneous intervention (PCI), ST-elevation infarction (STEMI) setting. Methods: One-hundred consecutive underwent PCI, with MGS deployment STEMI, five different high-volume PCI centres. Sixteen presented cardiogenic shock at admission. Results: All successful procedures: mean TIMI flow grade corrected frame count—cTFC(n)—improved from baseline values to 2.85 ± 0.40 17.20 10.51, respectively, a difference cTFC(n) between postprocedure of 46.88 31.86. High-myocardial blush (90% MBG 3; 10% 2) was also achieved all patients. Sixty minutes post-PCI, high rate (90%) complete (≥70%) ST-segment resolution achieved. At seven deaths occurred: noteworthy, 5 16 admission died. After hospital discharge, no Major Adverse Cardiac Events have been reported up 30-day follow-up. Conclusions: might represent safe feasible option patients, providing perfusional improvement. Further randomized trials comparing this strategy conventional one are needed near future assess impact on practice strategy. © 2009 Wiley-Liss, Inc.