The Preparation of Amines by Reductive Alkylation

摘要: Reductive alkylation is the term applied to process of introducing alkyl groups into ammonia or primary secondary amine by means an aldehdye ketone in presence a reducing agent. This chapter limited those reductive alkylations which agent hydrogen and catalysts nascent hydrogen, usually from metal-acid combination; most these have been carried out with catalyst. Keywords: amines; reductive alkylation; aldehdyes; ketones; ammonia; Schiff's base; primary amines; secondary amines; tertiary amines; experimental conditions