Inhibition of novel reassortant avian influenza H7N9 virus infection in vitro with three antiviral drugs, oseltamivir, peramivir and favipiravir.
作者： Rui-Yuan Cao , Jun-Hai Xiao , Bin Cao , Song Li , Yohichi Kumaki
DOI: 10.3851/IMP2672
关键词:
摘要: Background:A novel reassortant avian-origin influenza A (H7N9) virus was isolated from respiratory specimens obtained three patients and identified as H7N9 in China. Antiviral agents are required to treat with avian infection.Methods:In this study, we assessed the antiviral potential of oseltamivir, peramivir, favipiravir (T-705), amantadine rimantadine against vitro.Results:All strains were sensitive peramivir but resistant rimantadine.Conclusions:Our data show a pattern sensitivity for strain that suggests compounds should be useful therapy.
sagepub.com
intmedpress.com参考文章(15)
John Treanor, Frederick G Hayden, Luis Barroso, Larisa Gubareva, Efficacy and tolerability of the oral neuraminidase inhibitor peramivir in experimental human influenza: randomized, controlled trials for prophylaxis and treatment. Antiviral Therapy. ,vol. 10, pp. 901- 910 ,(2005)
Update on avian influenza A (H5N1) virus infection in humans. The New England Journal of Medicine. ,vol. 358, pp. 261- 273 ,(2008) , 10.1056/NEJMRA0707279
M Eickmann, C Drosten, M Eschbach-Bludau, M Matrosovich, V M Corman, S Brünink, S Becker, T Bleicker, O Landt, Specific detection by real-time reverse-transcription PCR assays of a novel avian influenza A(H7N9) strain associated with human spillover infections in China Eurosurveillance. ,vol. 18, pp. 20461- 20461 ,(2013) , 10.2807/ESE.18.16.20461-EN
Frederick G. Hayden, Robert L. Atmar, Margo Schilling, Casey Johnson, Donald Poretz, David Paar, Les Huson, Penelope Ward, Roger G. Mills, Use of the selective oral neuraminidase inhibitor oseltamivir to prevent influenza. The New England Journal of Medicine. ,vol. 341, pp. 1336- 1343 ,(1999) , 10.1056/NEJM199910283411802
Larisa V. Gubareva, Robert G. Webster, Frederick G. Hayden, Comparison of the Activities of Zanamivir, Oseltamivir, and RWJ-270201 against Clinical Isolates of Influenza Virus and Neuraminidase Inhibitor-Resistant Variants Antimicrobial Agents and Chemotherapy. ,vol. 45, pp. 3403- 3408 ,(2001) , 10.1128/AAC.45.12.3403-3408.2001
Xiaoli Xiong, Stephen R. Martin, Lesley F. Haire, Stephen A. Wharton, Rodney S. Daniels, Michael S. Bennett, John W. McCauley, Patrick J. Collins, Philip A. Walker, John J. Skehel, Steven J. Gamblin, Receptor Binding by an H7N9 Influenza Virus from Humans Nature. ,vol. 499, pp. 496- 499 ,(2013) , 10.1038/NATURE12372
M. Kiso, K. Takahashi, Y. Sakai-Tagawa, K. Shinya, S. Sakabe, Q. M. Le, M. Ozawa, Y. Furuta, Y. Kawaoka, T-705 (favipiravir) activity against lethal H5N1 influenza A viruses. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 107, pp. 882- 887 ,(2010) , 10.1073/PNAS.0909603107
Frederick G. Hayden, John J. Treanor, R. Scott Fritz, Monica Lobo, Robert F. Betts, Madeline Miller, Nelson Kinnersley, Roger G. Mills, Penelope Ward, Stephen E. Straus, Use of the oral neuraminidase inhibitor oseltamivir in experimental human influenza: randomized controlled trials for prevention and treatment. JAMA. ,vol. 282, pp. 1240- 1246 ,(1999) , 10.1001/JAMA.282.13.1240
Rongbao Gao, Bin Cao, Yunwen Hu, Zijian Feng, Dayan Wang, Wanfu Hu, Jian Chen, Zhijun Jie, Haibo Qiu, Ke Xu, Xuewei Xu, Hongzhou Lu, Wenfei Zhu, Zhancheng Gao, Nijuan Xiang, Yinzhong Shen, Zebao He, Yong Gu, Zhiyong Zhang, Yi Yang, Xiang Zhao, Lei Zhou, Xiaodan Li, Shumei Zou, Ye Zhang, Xiyan Li, Lei Yang, Junfeng Guo, Jie Dong, Qun Li, Libo Dong, Yun Zhu, Tian Bai, Shiwen Wang, Pei Hao, Weizhong Yang, Yanping Zhang, Jun Han, Hongjie Yu, Dexin Li, George F. Gao, Guizhen Wu, Yu Wang, Zhenghong Yuan, Yuelong Shu, Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus The New England Journal of Medicine. ,vol. 368, pp. 1888- 1897 ,(2013) , 10.1056/NEJMOA1304459
Y. Furuta, K. Takahashi, Y. Fukuda, M. Kuno, T. Kamiyama, K. Kozaki, N. Nomura, H. Egawa, S. Minami, Y. Watanabe, H. Narita, K. Shiraki, In Vitro and In Vivo Activities of Anti-Influenza Virus Compound T-705 Antimicrobial Agents and Chemotherapy. ,vol. 46, pp. 977- 981 ,(2002) , 10.1128/AAC.46.4.977-981.2002