NKp46 defines a subset of bovine leukocytes with natural killer cell characteristics.

作者: Anne K. Storset , Siri Kulberg , Ingvild Berg , Preben Boysen , Jayne C. Hope

DOI: 10.1002/EJI.200324504

关键词:

摘要: cells in cattle was compatible with the tissue distribution of NK other species. Bovine NKp46 + had typical, large granular lymphocyte morphology, and proliferated vigorously response to bovine IL-2 for a limited number cell divisions. IL-2-activated killed kidney line MDBK. This cytotoxicity inhibited by preincubation antibody against NKp46. In redirected lysis assay, Fc R tar- get P815 after Together, these data indi- cate that is an activating receptor demonstrate existence subset leukocytes that, terms surface markers, morphology function, represent cells.

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