Irreversible inhibitors and activity-based probes as research tools in chemical glycobiology

作者: Martin D Witte , Gijsbert A van der Marel , Johannes MFG Aerts , Herman S Overkleeft , None

DOI: 10.1039/C1OB05531C

关键词:

摘要: In this review, we will discuss the enzymes that are involved in the synthesis and degradation of glycoconjugates and we will give an overview of the inhibitors and activity …

参考文章(146)
John C. Christianson, Thomas A. Shaler, Ryan E. Tyler, Ron R. Kopito, OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD. Nature Cell Biology. ,vol. 10, pp. 272- 282 ,(2008) , 10.1038/NCB1689
M.M. Hermans, M.A. Kroos, J. van Beeumen, B.A. Oostra, A.J. Reuser, Human lysosomal alpha-glucosidase. Characterization of the catalytic site. Journal of Biological Chemistry. ,vol. 266, pp. 13507- 13512 ,(1991) , 10.1016/S0021-9258(18)92727-4
V Kaartinen, J C Williams, J Tomich, J R Yates, L E Hood, I Mononen, Glycosaparaginase from human leukocytes. Inactivation and covalent modification with diazo-oxonorvaline. Journal of Biological Chemistry. ,vol. 266, pp. 5860- 5869 ,(1991) , 10.1016/S0021-9258(19)67677-5
John M. Risley, De Hua Huang, Jerry J. Kaylor, Jayshri J. Malik, Yuan-Qing Xia, W.Michael York, Glycosylasparaginase activity requires the alpha-carboxyl group, but not the alpha-amino group, on N(4)-(2-Acetamido-2-deoxy-beta-D-glucopyranosyl)-L-asparagine. Archives of Biochemistry and Biophysics. ,vol. 391, pp. 165- 170 ,(2001) , 10.1006/ABBI.2001.2416
Nathan N. Aronson, Michael J. Kuranda, Lysosomal degradation of Asn-linked glycoproteins. The FASEB Journal. ,vol. 3, pp. 2615- 2622 ,(1989) , 10.1096/FASEBJ.3.14.2531691
Wenjun Du, John M. Risley, Acylation is rate-limiting in glycosylasparaginase-catalyzed hydrolysis of N4-(4′-substituted phenyl)-L-asparagines Organic and Biomolecular Chemistry. ,vol. 1, pp. 1900- 1905 ,(2003) , 10.1039/B301513K
Elaine W. S. Chan, Souvik Chattopadhaya, Resmi C. Panicker, Xuan Huang, Shao Q. Yao, Developing photoactive affinity probes for proteomic profiling: hydroxamate-based probes for metalloproteases. Journal of the American Chemical Society. ,vol. 126, pp. 14435- 14446 ,(2004) , 10.1021/JA047044I
Martijn Verdoes, Bogdan I. Florea, Victoria Menendez-Benito, Christa J. Maynard, Martin D. Witte, Wouter A. van der Linden, Adrianus M.C.H. van den Nieuwendijk, Tanja Hofmann, Celia R. Berkers, Fijs W.B. van Leeuwen, Tom A. Groothuis, Michiel A. Leeuwenburgh, Huib Ovaa, Jacques J. Neefjes, Dmitri V. Filippov, Gijs A. van der Marel, Nico P. Dantuma, Herman S. Overkleeft, A Fluorescent Broad-Spectrum Proteasome Inhibitor for Labeling Proteasomes In Vitro and In Vivo Chemistry & Biology. ,vol. 13, pp. 1217- 1226 ,(2006) , 10.1016/J.CHEMBIOL.2006.09.013
Elizabeth R Butch, Kun-Liang Guan, None, Characterization of ERK1 Activation Site Mutants and the Effect on Recognition by MEK1 and MEK2 Journal of Biological Chemistry. ,vol. 271, pp. 4230- 4235 ,(1996) , 10.1074/JBC.271.8.4230