Galacto configured N-aminoaziridines: a new type of irreversible inhibitor of β-galactosidases.
作者： Anna Alcaide , Ana Trapero , Yolanda Pérez , Amadeu Llebaria
DOI: 10.1039/C5OB00532A
关键词:
摘要: A new type of galactose mimetics has been synthesized following a straightforward synthetic approach based on cyclohexene olefin aziridination reactions directed by hydroxyl substituents. These enantiomerically pure galacto-configured N-aminoaziridines are potent irreversible inhibitors Aspergillus oryzae and Escherichia coli β-galactosidases.
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