Epidemiology of and risk factors for neonatal candidemia at a tertiary care hospital in western China.
作者： Jichang Chen , Yongjiang Jiang , Ba Wei , Yanling Ding , Shaolin Xu
DOI: 10.1186/S12879-016-2042-9
关键词:
摘要: The prevalence and clinical characteristics of neonatal candidemia are poorly understood in western China. aim our study was to evaluate the epidemiological features Liuzhou Maternity Child Healthcare Hospital. A retrospective case-control conducted between January 2012 November 2015. Electronic databases were reviewed data on Candida species isolated from blood cultures incidence, risk factors, mortality extracted. Univariate multivariate logistic regression analysis performed identify factors associated with candidemia. During 4-year period, identified 69 newborns, for an incidence rate 13.6 per 1000 admissions. Prolonged antibiotic therapy duration [odds ratio (OR), 95% confidence (95% CI) = 1.06, 1.01–1.10], total parenteral nutrition [OR, CI = 6.03, 2.10–17.30] neurodevelopmental impairment (OR, CI = 7.34, 1.18–45.80) all increased odds development infants (P value 0.010, 0.001, 0.033, respectively). overall 7.2% group. therapy, presence major This highlights importance early detection, diagnosis treatment
biomedcentral.com
springer.com
core.ac.uk
paperity.org参考文章(24)
Y F Liu, Y M Li, C L Dai, G H Wang, Cerebral and renal abscess and retino-choroiditis secondary to Candida albicans in preterm infants: eight case retrospective study. Clinical and Experimental Obstetrics & Gynecology. ,vol. 40, pp. 519- 523 ,(2013)
Jiahui Chen, Xiaodan Yu, Yijun Zhou, Yongjun Zhang, Jianxing Zhu, Lijuan Xie, Jihong Qian, Qingnan Yang, Hongping Xia, Tianwen Zhu, Yonghong Zhang, Yan Chen, Dongying Zhao, Zhenjuan He, Integrated measures for prevention of invasive Candida infections in preterm infants in a Chinese neonatal intensive care unit American Journal of Infection Control. ,vol. 43, pp. 1321- 1325 ,(2015) , 10.1016/J.AJIC.2015.07.011
R John Baier, John Loggins, Krishna Yanamandra, IL-10, IL-6 and CD14 polymorphisms and sepsis outcome in ventilated very low birth weight infants BMC Medicine. ,vol. 4, pp. 10- 10 ,(2006) , 10.1186/1741-7015-4-10
C Oeser, S Vergnano, R Naidoo, M Anthony, J Chang, P Chow, P Clarke, N Embleton, N Kennea, S Pattnayak, B Reichert, T Scorrer, I Tiron, T Watts, M Sharland, PT Heath, Neonatal Infection Surveillance Network (neonIN), Neonatal invasive fungal infection in England 2004–2010 Clinical Microbiology and Infection. ,vol. 20, pp. 936- 941 ,(2014) , 10.1111/1469-0691.12578
Daniel K Benjamin Jr, Barbara J Stoll, Avory A Fanaroff, Scott A McDonald, William Oh, Rosemary D Higgins, Shahnaz Duara, Kenneth Poole, Abbot Laptook, Ronald Goldberg, National Institute of Child Health and Human Development Neonatal Research Network, None, Neonatal Candidiasis Among Extremely Low Birth Weight Infants: Risk Factors, Mortality Rates, and Neurodevelopmental Outcomes at 18 to 22 Months Pediatrics. ,vol. 117, pp. 84- 92 ,(2006) , 10.1542/PEDS.2004-2292
Olivier Lortholary, Marie Desnos-Ollivier, Karine Sitbon, Arnaud Fontanet, Stéphane Bretagne, Françoise Dromer, Recent Exposure to Caspofungin or Fluconazole Influences the Epidemiology of Candidemia: a Prospective Multicenter Study Involving 2,441 Patients Antimicrobial Agents and Chemotherapy. ,vol. 55, pp. 532- 538 ,(2011) , 10.1128/AAC.01128-10
Zengbin Wu, Yingbin Liu, Xiaobo Feng, Ying Liu, Shuyun Wang, Xiaodong Zhu, Qiqi Chen, Shuming Pan, None, Candidemia: incidence rates, type of species, and risk factors at a tertiary care academic hospital in China International Journal of Infectious Diseases. ,vol. 22, pp. 4- 8 ,(2014) , 10.1016/J.IJID.2013.11.011
Joanna Filioti, Kleomenis Spiroglou, Emmanuel Roilides, Invasive candidiasis in pediatric intensive care patients: epidemiology, risk factors, management, and outcome Intensive Care Medicine. ,vol. 33, pp. 1272- 1283 ,(2007) , 10.1007/S00134-007-0672-5
Ira Adams-Chapman, Carla M Bann, Abhik Das, Ronald N Goldberg, Barbara J Stoll, Michele C Walsh, Pablo J Sánchez, Rosemary D Higgins, Seetha Shankaran, Kristi L Watterberg, Shahnaz Duara, Nancy A Miller, Roy J Heyne, Myriam Peralta-Carcelen, Ricki F Goldstein, Jean J Steichen, Charles R Bauer, Susan R Hintz, Patricia W Evans, Michael J Acarregui, Gary J Myers, Betty R Vohr, Deanne E Wilson-Costello, Athina Pappas, Yvonne E Vaucher, Richard A Ehrenkranz, Elisabeth C McGowan, Robert G Dillard, Janell Fuller, Daniel K Benjamin Jr, None, Neurodevelopmental Outcome of Extremely Low Birth Weight Infants with Candida Infection The Journal of Pediatrics. ,vol. 163, pp. 961- 967 ,(2013) , 10.1016/J.JPEDS.2013.04.034
G Natarajan, M Lulic-Botica, J V Aranda, Refractory neonatal candidemia and high-dose micafungin pharmacotherapy. Journal of Perinatology. ,vol. 29, pp. 738- 743 ,(2009) , 10.1038/JP.2009.75