Cerebral and renal abscess and retino-choroiditis secondary to Candida albicans in preterm infants: eight case retrospective study.

摘要: Objectives To assess the tissues and organs commonly involved clinical features in invasive fungal infection (IFI) of Candida albicans preterm infants. Materials methods Eight infants who developed IFI with positive blood culture for were retrospectively studied. All received selected laboratory parameters evaluation, such as culture, cerebral magnetic resonance imaging (MRI), cerebrospinal fluid (CSF) biochemical test, routine urine renal ultrasonography, computer tomography (CT), fundus examination. The re-examinations performed after one to two months follow-up. Results Cerebral abscesses detected six Five cases systemic infection, among which had abscess. Three complicated retino-choroiditis. Conclusions Preterm infants, especially very-low-birthweight (VLBW) extremely-low-birth-weight (ELBW) are susceptible fungi. majority late-onset infections due albicans. central nervous system (CNS), kidney fundus, prone recur, calling a prolonged anti-fungi treatment course.