Detecting optic nerve head deformation and retinal nerve fiber layer thinning in glaucoma progression.

摘要: The application of digital imaging technologies including confocal scanning laser ophthalmoscopy (CSLO), optical coherence tomography (OCT), and polarimetry (SLP) has significantly improved the detection optic nerve head (ONH) deformation progressive retinal fiber layer (RNFL) thinning for assessment glaucoma progression. Algorithms change analysis such as topographic guided progression perform event serial ONH surface height topology maps RNFL thickness/RNFL retardance maps, respectively, providing a topographical display location significant change. With spectral-domain OCT, it is feasible to delineate measure lamina cribrosa depth in addition thickness. Growing evidence from experimental clinical studies indicates that can be observed prior detectable functional loss glaucoma. These findings lend support notion upon ONH/lamina deformation, time window therapeutic intervention better outcomes may exist. are therefore important targets monitoring This review summarizes latest comparing performance CSLO, SLP damages patients implication limitations studying morphological alteration ONH, cribrosa,