LC-MS in Drug Metabolism and Pharmacokinetics: A Pharmaceutical Industry Perspective
作者： Wenying Jian , Wilson Shou , Richard W. Edom , Naidong Weng , Mingshe Zhu
DOI: 10.1002/9781118180730.CH6
关键词:
摘要:
sci-hub.se 参考文章(180)
Simon A Roberts, Drug metabolism and pharmacokinetics in drug discovery. Current Opinion in Drug Discovery & Development. ,vol. 6, pp. 66- 80 ,(2003)
Shuguang Ma, Swapan K. Chowdhury, Application of Liquid Chromatography/Mass Spectrometry for Metabolite Identification John Wiley & Sons, Inc.. pp. 319- 367 ,(2007) , 10.1002/9780470191699.CH11
N.J. White, N.P.J. Day, Development and validation of a liquid chromatographic-tandem mass spectrometric method for determination of piperaquine in plasma stable isotope labeled internal standard does not always compensate for matrix effects. Journal of Chromatography B. ,vol. 862, pp. 227- 236 ,(2008) , 10.1016/J.JCHROMB.2007.12.011
Wenying Jian, Ming Yao, Bo Wen, Elliott B. Jones, Mingshe Zhu, Use of Triple Quadrupole-Linear Ion Trap Mass Spectrometry as a Single LC-MS Platform in Drug Metabolism and Pharmacokinetics Studies Mass Spectrometry in Drug Metabolism and Disposition. pp. 483- 524 ,(2011) , 10.1002/9780470929278.CH15
J R Barr, V L Maggio, D G Patterson, G R Cooper, L O Henderson, W E Turner, S J Smith, W H Hannon, L L Needham, E J Sampson, Isotope dilution--mass spectrometric quantification of specific proteins: model application with apolipoprotein A-I. Clinical Chemistry. ,vol. 42, pp. 1676- 1682 ,(1996) , 10.1093/CLINCHEM/42.10.1676
Johan Gabrielsson, A. Richard Green, Piet H. Van der Graaf, Optimising in vivo pharmacology studies—Practical PKPD considerations Journal of Pharmacological and Toxicological Methods. ,vol. 61, pp. 146- 156 ,(2010) , 10.1016/J.VASCN.2010.02.002
Yunsheng Hsieh, Christine J. G. Duncan, Jean-Marc Brisson, Fused-Core Silica Column High-Performance Liquid Chromatography/Tandem Mass Spectrometric Determination of Rimonabant in Mouse Plasma Analytical Chemistry. ,vol. 79, pp. 5668- 5673 ,(2007) , 10.1021/AC070343G
Zhengyin Yan, Gary W. Caldwell, Noureddine Maher, Unbiased high-throughput screening of reactive metabolites on the linear ion trap mass spectrometer using polarity switch and mass tag triggered data-dependent acquisition. Analytical Chemistry. ,vol. 80, pp. 6410- 6422 ,(2008) , 10.1021/AC800887H
Mingshe Zhu, Haiying Zhang, W. Griffith Humphreys, Drug Metabolite Profiling and Identification by High-resolution Mass Spectrometry Journal of Biological Chemistry. ,vol. 286, pp. 25419- 25425 ,(2011) , 10.1074/JBC.R110.200055
Mohammed Jemal, High-throughput quantitative bioanalysis by LC/MS/MS. Biomedical Chromatography. ,vol. 14, pp. 422- 429 ,(2000) , 10.1002/1099-0801(200010)14:6<422::AID-BMC25>3.0.CO;2-I