Inflammation and the Microcirculation

摘要: Abstract The microcirculation is highly responsive to, and a vital participant in, the inflammatory response. All segments of microvasculature (arterioles, capillaries, venules) exhibit characteristic phenotypic changes during inflammation that appear to be directed toward enhancing delivery cells injured/infected tissue, isolating region from healthy tissue systemic circulation, setting stage for repair regeneration. best characterized responses include impaired vasomotor function, reduced capillary perfusion, adhesion leukocytes platelets, activation coagulation cascade, enhanced thrombosis, increased vascular permeability, an increase in rate proliferation blood lymphatic vessels. A variety normally circulate (leukocytes, platelets) or reside within vessel wall (endothelial cells, pericytes) perivascular space (mast cells,...