Analysis of world strains of Anaplasma marginale using major surface protein 1a repeat sequences.

摘要: Abstract Anaplasma marginale is a tick-borne pathogen of cattle that causes the disease bovine anaplasmosis worldwide. Major surface proteins (MSPs) are involved in host–pathogen and tick–pathogen interactions have been used as markers for genetic characterization A. strains phylogenetic studies. MSP1a adhesion transmission by ticks varies among geographic number sequence amino-terminal tandem repeats. The aim this study was to characterize diversity collected from countries North South America, Europe, Asia, Africa Australia, inclusive all continents. In study, we characterized 131 using 79 repeat sequences. These results corroborated heterogeneity endemic regions analyses sequences did not result clusters according origin but provided phylogeographic information. Seventy-eight percent were present single region. Strong (≥80%) support found containing Italian, Spanish, Chinese, Argentinean American strains. suggested co-evolution evidence multiple introductions various locations contribute understanding evolution interactions.