摘要: Nonsteroidal anti-inflammatory drugs such as aspirin have been used widely for decades but are associated with gastrointestinal side effects. The newer generation of drugs, the COX-2 selective inhibitors, do not effects, at least one them is reported to lead an increase in thrombotic events. In his Perspective, Vane discusses new findings ( Cheng et al .) that shed light on why inhibiting rather than both COX isoforms may dysregulation cardiovascular homeostasis.
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