OXA-48 and CTX-M-15 extended-spectrum beta-lactamases in raw milk in Lebanon: epidemic spread of dominant Klebsiella pneumoniae clones.
作者： Mohamad Diab , Monzer Hamze , Richard Bonnet , Estelle Saras , Jean-Yves Madec
DOI: 10.1099/JMM.0.000620
关键词:
摘要: Raw milk has recently been reported as a source of extended-spectrum beta-lactamase (ESBL) and carbapenemase genes. We thus investigated the prevalence ESBL- carbapenemase-producing Enterobacteriaceae in raw Lebanon order to assess risk transfer these bacteria humans. A high (30.2 %) CTX-M-15-producing K. pneumoniae was detected bovine milk. Three main clones were identified by PFGE MLST typing. Southern blot experiments revealed that one carried blaCTX-M-15 gene chromosomally. Moreover, OXA-48-producing ST530 seven Escherichia coli sharing same ST also detected. These findings highlight spread dominant isolates food chain. Milk, which is mostly consumed Lebanon, may be human exposure ESBLs carbapenemases.
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archives-ouvertes.fr参考文章(26)
Qiu-E. Yang, Jian Sun, Liang Li, Hui Deng, Bao-Tao Liu, Liang-Xing Fang, Xiao-Ping Liao, Ya-Hong Liu, IncF plasmid diversity in multi-drug resistant Escherichia coli strains from animals in China Frontiers in Microbiology. ,vol. 6, pp. 964- 964 ,(2015) , 10.3389/FMICB.2015.00964
A Potron, L Poirel, E Rondinaud, P Nordmann, Intercontinental spread of OXA-48 beta-lactamase-producing Enterobacteriaceae over a 11-year period, 2001 to 2011. Eurosurveillance. ,vol. 18, pp. 20549- ,(2013) , 10.2807/1560-7917.ES2013.18.31.20549
E. A. Reuland, N. al Naiemi, S. A. Raadsen, P. H. M. Savelkoul, J. A. J. W. Kluytmans, C. M. J. E. Vandenbroucke-Grauls, Prevalence of ESBL-producing Enterobacteriaceae in raw vegetables European Journal of Clinical Microbiology & Infectious Diseases. ,vol. 33, pp. 1843- 1846 ,(2014) , 10.1007/S10096-014-2142-7
Laurent Poirel, Timothy R. Walsh, Vincent Cuvillier, Patrice Nordmann, Multiplex PCR for detection of acquired carbapenemase genes Diagnostic Microbiology and Infectious Disease. ,vol. 70, pp. 119- 123 ,(2011) , 10.1016/J.DIAGMICROBIO.2010.12.002
ALENA SKOČKOVÁ, KATEŘINA BOGDANOVIČOVÁ, IVANA KOLÁČKOVÁ, RENÁTA KARPÍŠKOVÁ, Antimicrobial-resistant and extended-spectrum β-lactamase-producing Escherichia coli in raw cow's milk. Journal of Food Protection. ,vol. 78, pp. 72- 77 ,(2015) , 10.4315/0362-028X.JFP-14-250
Iren Høyland Löhr, Nils Hülter, Eva Bernhoff, Pål Jarle Johnsen, Arnfinn Sundsfjord, Umaer Naseer, None, Persistence of a pKPN3-Like CTX-M-15-Encoding IncFIIK Plasmid in a Klebsiella pneumonia ST17 Host during Two Years of Intestinal Colonization PLOS ONE. ,vol. 10, pp. e0116516- ,(2015) , 10.1371/JOURNAL.PONE.0116516
Siren Rettedal, Iren H. Löhr, Olav Natås, Christian G. Giske, Arnfinn Sundsfjord, Knut Øymar, First outbreak of extended‐spectrum β‐lactamase‐producing Klebsiella pneumoniae in a Norwegian neonatal intensive care unit; associated with contaminated breast milk and resolved by strict cohorting Apmis. ,vol. 120, pp. 612- 621 ,(2012) , 10.1111/J.1600-0463.2012.02879.X
Alessandra Carattoli, Alessia Bertini, Laura Villa, Vincenzo Falbo, Katie L. Hopkins, E. John Threlfall, Identification of plasmids by PCR-based replicon typing Journal of Microbiological Methods. ,vol. 63, pp. 219- 228 ,(2005) , 10.1016/J.MIMET.2005.03.018
Katrin Zurfluh, Magdalena Nüesch-Inderbinen, Marina Morach, Annina Zihler Berner, Herbert Hächler, Roger Stephan, Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae Isolated from Vegetables Imported from the Dominican Republic, India, Thailand, and Vietnam Applied and Environmental Microbiology. ,vol. 81, pp. 3115- 3120 ,(2015) , 10.1128/AEM.00258-15
Mirnawati Sudarwanto, Ömer Akineden, Sabrina Odenthal, Madeleine Gross, Ewald Usleber, Extended-Spectrum β-Lactamase (ESBL)–Producing Klebsiella pneumoniae in Bulk Tank Milk from Dairy Farms in Indonesia Foodborne Pathogens and Disease. ,vol. 12, pp. 585- 590 ,(2015) , 10.1089/FPD.2014.1895