Sample collection, biobanking, and analysis.

摘要: Pediatric pharmacokinetic studies require sampling of biofluids from neonates and children. Limitations on frequency sample volume complicate the design these studies. In addition, strict guidelines, designed to guarantee patient safety, are in place. This chapter describes practical implications collection their storage, with special focus selection appropriate type biofluid withdrawal technique. we describe measures for storage specimens, example, context biobanking, requirements drug assay methods that they pose. Pharmacokinetic children possible, but careful an method, specimen volume, method. The checklist provided could help prospective researchers study protocol infrastructure.