The mammalian Golgi apparatus during M-phase

作者: Tom Misteli

DOI: 10.1007/978-1-4615-5873-6_24

关键词:

摘要: The Golgi apparatus in mammalian cells disassembles into several thousand vesicles as enter M-phase. Disassembly is dependent on the action of cdc2-kinase and at least two pathways contribute to fragmentation: One involves budding COP-coated from cisternae with concomitant inhibition fusion their target membranes, other a less well characterised COP-independent pathway. During telophase, fragments reassemble fuse fully functional stack, using distinct pathways. morphological changes during M-phase offer an ideal system study how cellular organelles are generated structure maintained interphase.

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