Does chemotherapy improve survival in advanced breast cancer? A statistical overview.

摘要: The relative efficacies of cytotoxic chemotherapy regimens in the treatment advanced breast cancer are generally assessed by comparing response rates randomised trials. Treatment attempts to prolong survival but trials rarely demonstrate a statistically significant advantage: it has been argued that does not survival. correlation between and examined reviewing 79 comparisons arms with unequal 50 published cancer. In 73% group higher rate also demonstrated longer median (P less than 0.001). Weighted linear regression showed relationship number patients comparison did influence this relationship.