作者: Katsuhiko Fujii , Shigehisa Kitahara , Takayuki Ozawa , Satoru Sugiyama
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摘要: The present invention provides a preventive or therapeutic agent for tissue injury caused by active oxygens and free radicals, having its effective component γ-L-glutamyl-L-cysteine ester derivative indicated in the following general formula: ##STR1## wherein, R is straight chain, branched cyclical hydrocarbon group 1-10 carbon atoms, chain 1-carbons substituted with an aromatic group, oxidized dimer. This compound has effect of elevating glutathione levels biochemically substitute thereby performing effects against ischemia-reperfusion heart, liver other organs, arrhythmia, as well lung radicals.