Species-Independent Modeling of High-Frequency Ultrasound Backscatter in Hyaline Cartilage.
作者： Nils Männicke , Martin Schöne , Jukka Liukkonen , Dominik Fachet , Satu Inkinen
DOI: 10.1016/J.ULTRASMEDBIO.2016.01.018
关键词:
摘要: Apparent integrated backscatter (AIB) is a common ultrasound parameter used to assess cartilage matrix degeneration. However, the specific contributions of chondrocytes, proteoglycan and collagen AIB remain unknown. To reveal these relationships, this work examined biopsies cross sections human, ovine bovine with 40-MHz biomicroscopy. Site-matched estimates concentration, orientation cell number density were employed in quasi-least-squares linear regression analyses model AIB. A positive correlation (R(2) = 0.51, p 70°) sound beam direction. These findings indicate causal relationships between cartilage structural parameters could aid more sophisticated future interpretations backscatter.
uq.edu.au参考文章(39)
H J Mankin, J A Buckwalter, Articular cartilage: degeneration and osteoarthritis, repair, regeneration, and transplantation. Journal of Bone and Joint Surgery, American Volume. ,vol. 47, pp. 487- 504 ,(1998)
Joseph M. Hilbe, Justine Shults, Quasi-Least Squares Regression ,(2014)
Sarah J. Ratcliffe, Justine Shults, GEEQBOX: A MATLAB Toolbox for Generalized Estimating Equations and Quasi-Least Squares Journal of Statistical Software. ,vol. 25, pp. 1- 14 ,(2008) , 10.18637/JSS.V025.I14
Heikki J. Nieminen, Simo Saarakkala, Mikko S. Laasanen, Jani Hirvonen, Jukka S. Jurvelin, Juha Töyräs, Ultrasound attenuation in normal and spontaneously degenerated articular cartilage. Ultrasound in Medicine and Biology. ,vol. 30, pp. 493- 500 ,(2004) , 10.1016/J.ULTRASMEDBIO.2003.12.007
Emmanuel Chérin, Amena Säıed, Pascal Laugier, Patrick Netter, Geneviève Berger, Evaluation of acoustical parameter sensitivity to age-related and osteoarthritic changes in articular cartilage using 50-MHz ultrasound. Ultrasound in Medicine and Biology. ,vol. 24, pp. 341- 354 ,(1998) , 10.1016/S0301-5629(97)00289-5
E. Chérin, A. Saı̈ed, B. Pellaumail, D. Loeuille, P. Laugier, P. Gillet, P. Netter, G. Berger, Assessment of rat articular cartilage maturation using 50-MHz quantitative ultrasonography Osteoarthritis and Cartilage. ,vol. 9, pp. 178- 186 ,(2001) , 10.1053/JOCA.2000.0374
Lassi Rieppo, Jarno Rieppo, Jukka S. Jurvelin, Simo Saarakkala, Fourier Transform Infrared Spectroscopic Imaging and Multivariate Regression for Prediction of Proteoglycan Content of Articular Cartilage PLoS ONE. ,vol. 7, pp. e32344- ,(2012) , 10.1371/JOURNAL.PONE.0032344
J. Liukkonen, J. Hirvasniemi, A. Joukainen, P. Penttilä, T. Virén, S. Saarakkala, H. Kröger, J.S. Jurvelin, J. Töyräs, Arthroscopic ultrasound technique for simultaneous quantitative assessment of articular cartilage and subchondral bone: an in vitro and in vivo feasibility study. Ultrasound in Medicine and Biology. ,vol. 39, pp. 1460- 1468 ,(2013) , 10.1016/J.ULTRASMEDBIO.2013.03.026
N. Männicke, M. Schöne, M. Oelze, K. Raum, Articular cartilage degeneration classification by means of high-frequency ultrasound. Osteoarthritis and Cartilage. ,vol. 22, pp. 1577- 1582 ,(2014) , 10.1016/J.JOCA.2014.06.019
Nils Männicke, Martin Schöne, Matthias Gottwald, Felix Göbel, Michael L. Oelze, Kay Raum, 3-D High-Frequency Ultrasound Backscatter Analysis of Human Articular Cartilage Ultrasound in Medicine and Biology. ,vol. 40, pp. 244- 257 ,(2014) , 10.1016/J.ULTRASMEDBIO.2013.08.015