Knockdown of thioredoxin-interacting protein ameliorates high glucose-induced epithelial to mesenchymal transition in renal tubular epithelial cells.

作者: Jinying Wei , Yonghong Shi , Yanjuan Hou , Yunzhuo Ren , Chunyang Du

DOI: 10.1016/J.CELLSIG.2013.09.009

关键词:

摘要: … -induced renal dysfunction is the EMT, which contributes to the generation of renal fibrosis [6]. … In the present study, we examined the expression of TXNIP in high glucose-treated HK-2 …

参考文章(41)
Yonghong Shi, Yunzhuo Ren, Lijuan Zhao, Chunyang Du, Yuehua Wang, Yanling Zhang, Ying Li, Song Zhao, Huijun Duan, Knockdown of thioredoxin interacting protein attenuates high glucose‐induced apoptosis and activation of ASK1 in mouse mesangial cells FEBS Letters. ,vol. 585, pp. 1789- 1795 ,(2011) , 10.1016/J.FEBSLET.2011.04.021
Sho-Ichi Yamagishi, Yosuke Inagaki, Tamami Okamoto, Shinjiro Amano, Kohachiro Koga, Masayoshi Takeuchi, Advanced glycation end products inhibit de novo protein synthesis and induce TGF-β overexpression in proximal tubular cells Kidney International. ,vol. 63, pp. 464- 473 ,(2003) , 10.1046/J.1523-1755.2003.00752.X
Lin Sun, Vinay K. Kondeti, Ping Xie, Kirtee Raparia, Yashpal S. Kanwar, Epac1-Mediated, High Glucose–Induced Renal Proximal Tubular Cells Hypertrophy via the Akt/p21 Pathway The American Journal of Pathology. ,vol. 179, pp. 1706- 1718 ,(2011) , 10.1016/J.AJPATH.2011.06.035
Edgar A. Jaimes, Josep Maria Galceran, Leopoldo Raij, Angiotensin II induces superoxide anion production by mesangial cells Kidney International. ,vol. 54, pp. 775- 784 ,(1998) , 10.1046/J.1523-1755.1998.00068.X
Rohan Samarakoon, Amy D. Dobberfuhl, Catherine Cooley, Jessica M. Overstreet, Samik Patel, Roel Goldschmeding, Kirstan K. Meldrum, Paul J. Higgins, Induction of renal fibrotic genes by TGF-β1 requires EGFR activation, p53 and reactive oxygen species Cellular Signalling. ,vol. 25, pp. 2198- 2209 ,(2013) , 10.1016/J.CELLSIG.2013.07.007
Yunzhuo Ren, Yonghong Shi, Yuehua Wang, Yingmin Li, Shuhui Wu, Hang Li, Yanling Zhang, Huijun Duan, p38 MAPK pathway is involved in high glucose-induced thioredoxin interacting protein induction in mouse mesangial cells FEBS Letters. ,vol. 584, pp. 3480- 3485 ,(2010) , 10.1016/J.FEBSLET.2010.07.010
Seung Hyun Han, Jun Ho Jeon, Hyang Ran Ju, Uhee Jung, Kun Young Kim, Hyang Sook Yoo, Young Ho Lee, Kyu Sang Song, Ho Myeung Hwang, Yoon Sook Na, Young Yang, Kee Nyung Lee, Inpyo Choi, VDUP1 upregulated by TGF-β1 and 1,25-dihydorxyvitamin D3 inhibits tumor cell growth by blocking cell-cycle progression Oncogene. ,vol. 22, pp. 4035- 4046 ,(2003) , 10.1038/SJ.ONC.1206610
Richard E. Gilbert, Mark E. Cooper, The tubulointerstitium in progressive diabetic kidney disease: More than an aftermath of glomerular injury? Kidney International. ,vol. 56, pp. 1627- 1637 ,(1999) , 10.1046/J.1523-1755.1999.00721.X
Anu Shah, Ling Xia, Howard Goldberg, Ken W. Lee, Susan E. Quaggin, I. George Fantus, Thioredoxin-interacting Protein Mediates High Glucose-induced Reactive Oxygen Species Generation by Mitochondria and the NADPH Oxidase, Nox4, in Mesangial Cells Journal of Biological Chemistry. ,vol. 288, pp. 6835- 6848 ,(2013) , 10.1074/JBC.M112.419101