A Potent and Orally Active Antagonist (SM-406/AT-406) of Multiple Inhibitor of Apoptosis Proteins (IAPs) in Clinical Development for Cancer Treatment
作者： Qian Cai , Haiying Sun , Yuefeng Peng , Jianfeng Lu , Zaneta Nikolovska-Coleska
DOI: 10.1021/JM101505D
关键词:
摘要: We report the discovery and characterization of SM-406 (compound 2), a potent and orally bioavailable Smac mimetic and an antagonist of the inhibitor of apoptosis proteins (IAPs). …
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