Platinum(II) complexes with N-monoalkyl 1R,2R-diaminocyclohexane derivatives as carrier ligands and 3-hydroxycyclobutane-1,1-dicarboxylate as a leaving group: potent cytotoxicity and DNA binding ability.
作者： Lei Fang , Shaohua Gou , Jian Zhao , Yanyan Sun , Lin Cheng
DOI: 10.1016/J.EJMECH.2013.07.004
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摘要: … –activity-relationship theory of platinum-based drugs the … lipophilicity and hydrophilicity of platinum complexes. Considering … and benefit the DNA-bonding ability of the complexes via a H…
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