Cathepsin B-sensitive dipeptide prodrugs. 2. Models of anticancer drugs paclitaxel (Taxol®), mitomycin C and doxorubicin
作者： Gene M. Dubowchik , Kathleen Mosure , Jay O. Knipe , Raymond A. Firestone
DOI: 10.1016/S0960-894X(98)00610-6
关键词:
摘要: … by cathepsin B to release free DOX and are very stable in human plasma. 7 The self-immolative PABC spacer 8 is required for drug release… , their drug release behavior with cathepsin B …
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