Association of ADAM33 gene polymorphisms with adult allergic asthma and rhinitis in a Chinese Han population

作者: Dongju Su , Ximei Zhang , Hong Sui , Fuzhen Lü , Lianhong Jin

DOI: 10.1186/1471-2350-9-82

关键词:

摘要: Background Rhinitis and asthma are very common diseases involving genetic environmental factors. Most patients with also have rhinitis, which suggests the concept of 'one airway, one disease.' A disintegrin metalloproteinase 33 (ADAM33) is first asthma-susceptible gene to be discovered by positional cloning. To evaluate potential influence ADAM33 polymorphisms on allergic rhinitis (AR) (AS), a case-control study was conducted Han population northeast China.

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