Fresh blastocyst transfer as a clinical approach to overcome the detrimental effect of progesterone elevation at hCG triggering: a strategy in the context of the Italian law.

作者: Laura Corti , Enrico Papaleo , Luca Pagliardini , Elisa Rabellotti , Michela Molgora

DOI: 10.1016/J.EJOGRB.2013.08.017

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摘要: Abstract Objective To retrospectively evaluate whether fresh day-5 embryo transfer could overcomes the detrimental effect of subtle progesterone elevations at hCG administration on pregnancy outcomes in women undergoing ovarian hyperstimulation for IVF/ICSI cycles. Study design Retrospective study 204 infertile patients aged 23–44 years who underwent treatment and blastocyst under Italian law (embryos cryopreservation cannot be planned advance). Women were divided into those with a level Results Age, body mass index (BMI), antral follicle count, anti-Mullerian hormone (AMH) FSH values, mean number stimulation days, ratio GnRH agonist antagonist cycles total dose gonadotrophins administered did not differ between two groups. Serum estradiol retrieved oocytes significantly increased group elevated higher was used this group. Fertilization rate, percentage top quality embryos, transferred blastocysts similar The CPR levels Conclusions A does completely overcome rise outcomes.

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