Evaluation of Patients with Epilepsy

摘要: The study of epilepsy may have contributed more to the understanding human brain-behavior relationships than any other central nervous system disorder (Novelly, 1992). J. Hughlings Jackson was among first scientists relate clinical or behavioral observations brain morphology (Reynolds, 1988). maintained it possible ascertain neuroanatomical location a focal seizure focus by observing physical progression (Haynes & Bennett, He subsequently developed hypothesis that caused abnormal discharges from lesions in brain, establishing theory has led our contemporary Further advances localization functioning were made through cortical stimulation performed on conscious patients undergoing neurosurgery for removal epileptogenic lesions. This procedure allowed development somatotopic maps peri-rolandic motor-sensory cortex and concept homunculus (Penfield Rasmussen, 1950). children hemispherectomies treat intractable plasticity speech language. Specifically, critical periods developing language transfer following hemispherectomy been identified (Goodman Whitaker, 1985). Models memory studied extensively temporal lobectomy hippocampus removal. Studies as early 1950s demonstrated link between bilateral mesial resection amnesia (Scoville Milner, 1957). Severe disturbance unilateral reported with suspected contralateral hippocampal zone 1958).