Performance of MACACO Compton telescope for ion-beam therapy monitoring: first test with proton beams

摘要: In order to exploit the advantages of ion-beam therapy in a clinical setting, delivery verification techniques are necessary detect deviations from planned treatment. Efforts currently oriented towards development devices for real-time range monitoring. Among different detector concepts proposed, Compton cameras employed prompt gammas and represent valid candidate verification. We present first on-beam test MACACO, telescope (multi-layer camera) based on lanthanum bromide crystals silicon photo-multipliers. The was characterized through measurements Monte Carlo simulations. linearity measured employing (22)Na Am-Be sources, obtaining about 10% deviation at 3.44 MeV. A spectral image reconstruction algorithm tested synthetic data. Point-like sources emitting gamma rays with energy between 2 7 MeV were reconstructed 3-5 mm resolution. two-layer measure radiation emitted beam 150 protons impinging cylindrical PMMA target. Bragg-peak shifts achieved via adjustment target location resulting used during reconstruction. Reconstructed Bragg peak profiles proved sufficient observe peak-location differences within 10 mm demonstrating potential MACACO Telescope as monitoring device therapy.