Influence of adrenalin on sugar transport in soleus, a red skeletal muscle

摘要: Abstract The effect of adrenalin on the transport nonmetabolized sugar, 3-methylglucose, was studied in isolated rat soleus. Basal sugar inhibited and Na + K gradients were increased by 10 −8 to −3 M adrenalin. Isoproterenol phenylephrine had same effects which due beta-adrenoceptor interaction. Adrenalin also inhibitory under anoxic conditions presence palmitate low levels insulin. External , or Ca 2+ not required for its data suggest that it involves a change apparent V max rather than m . Inhibition influx always paralleled lower internal levels, nor correlated with changes ATP G-6-P; this excludes several possible mechanisms effect. failure high concentrations stimulate (as diaphragm heart muscle) is attributed oxidative capacity red muscle.