Causes and consequences of RNA polymerase II stalling during transcript elongation.
作者： Melvin Noe Gonzalez , Daniel Blears , Jesper Q. Svejstrup
DOI: 10.1038/S41580-020-00308-8
关键词:
摘要: … Of the three RNA polymerases in eukaryotes, RNA polymerase II (Pol II) is responsible for the transcription of all protein-coding genes and a variety of non-coding RNAs. In a simplified …
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D. Reinberg, R.G. Roeder, Factors involved in specific transcription by mammalian RNA polymerase II. Transcription factor IIS stimulates elongation of RNA chains. Journal of Biological Chemistry. ,vol. 262, pp. 3331- 3337 ,(1987) , 10.1016/S0021-9258(18)61507-8
J. Rappaport, D. Reinberg, R. Zandomeni, R. Weinmann, Purification and functional characterization of transcription factor SII from calf thymus. Role in RNA polymerase II elongation. Journal of Biological Chemistry. ,vol. 262, pp. 5227- 5232 ,(1987) , 10.1016/S0021-9258(18)61178-0
D Reines, Elongation factor-dependent transcript shortening by template-engaged RNA polymerase II. Journal of Biological Chemistry. ,vol. 267, pp. 3795- 3800 ,(1992) , 10.1016/S0021-9258(19)50596-8
M.G. Izban, D.S. Luse, Factor-stimulated RNA polymerase II transcribes at physiological elongation rates on naked DNA but very poorly on chromatin templates. Journal of Biological Chemistry. ,vol. 267, pp. 13647- 13655 ,(1992) , 10.1016/S0021-9258(18)42262-4
Su Guo, Yuki Yamaguchi, Sarah Schilbach, Tadashi Wada, James Lee, Audrey Goddard, Dorothy French, Hiroshi Handa, Arnon Rosenthal, A regulator of transcriptional elongation controls vertebrate neuronal development Nature. ,vol. 408, pp. 366- 369 ,(2000) , 10.1038/35042590
D Reines, M J Chamberlin, C M Kane, Transcription elongation factor SII (TFIIS) enables RNA polymerase II to elongate through a block to transcription in a human gene in vitro. Journal of Biological Chemistry. ,vol. 264, pp. 10799- 10809 ,(1989) , 10.1016/S0021-9258(18)81692-1
Lynne Mayne, Alan R. Lehmann, Failure of RNA synthesis to recover after UV irradiation: an early defect in cells from individuals with Cockayne's syndrome and xeroderma pigmentosum Cancer Research. ,vol. 42, pp. 1473- 1478 ,(1982) , 10.1016/0027-5107(82)90047-1
Sylvie L. Beaudenon, Maria R. Huacani, Guangli Wang, Donald P. McDonnell, Jon M. Huibregtse, Rsp5 Ubiquitin-Protein Ligase Mediates DNA Damage-Induced Degradation of the Large Subunit of RNA Polymerase II in Saccharomyces cerevisiae Molecular and Cellular Biology. ,vol. 19, pp. 6972- 6979 ,(1999) , 10.1128/MCB.19.10.6972
Fan Lai, Alessandro Gardini, Anda Zhang, Ramin Shiekhattar, Integrator mediates the biogenesis of enhancer RNAs Nature. ,vol. 525, pp. 399- 403 ,(2015) , 10.1038/NATURE14906
A. Missra, D. S. Gilmour, Interactions between DSIF (DRB sensitivity inducing factor), NELF (negative elongation factor), and the Drosophila RNA polymerase II transcription elongation complex. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 107, pp. 11301- 11306 ,(2010) , 10.1073/PNAS.1000681107