DNA inoculation induces neutralizing immune responses against human immunodeficiency virus type 1 in mice and nonhuman primates.

作者: BAN WANG , JEAN BOYER , VASANTHA SRIKANTAN , LESLIE CONEY , RICHARD CARRANO

DOI: 10.1089/DNA.1993.12.799

关键词:

摘要: ABSTRACT DNA, or genetic, inoculation mimics aspects of attenuated vaccines in that synthesis specific foreign proteins is accomplished the host. These can be processed and presented...

参考文章(13)
D C Montefiori, W E Robinson, S S Schuffman, W M Mitchell, Evaluation of antiviral drugs and neutralizing antibodies to human immunodeficiency virus by a rapid and sensitive microtiter infection assay. Journal of Clinical Microbiology. ,vol. 26, pp. 231- 235 ,(1988) , 10.1128/JCM.26.2.231-235.1988
E. Nabel, G Plautz, G. Nabel, Site-specific gene expression in vivo by direct gene transfer into the arterial wall. Science. ,vol. 249, pp. 1285- 1288 ,(1990) , 10.1126/SCIENCE.2119055
M Kowalski, J Potz, L Basiripour, T Dorfman, W. Goh, E Terwilliger, A Dayton, C Rosen, W Haseltine, J Sodroski, Functional regions of the envelope glycoprotein of human immunodeficiency virus type 1 Science. ,vol. 237, pp. 1351- 1355 ,(1987) , 10.1126/SCIENCE.3629244
A. Srinivasan, R. Anand, D. York, P. Ranganathan, P. Feorino, G. Schochetman, J. Curran, V.S. Kalyanaraman, P.A. Luciw, R. Sanchez-Pescador, Molecular characterization of human immunodeficiency virus from Zaire: nucleotide sequence analysis identifies conserved and variable domains in the envelope gene Gene. ,vol. 52, pp. 71- 82 ,(1987) , 10.1016/0378-1119(87)90396-9
B. Wang, K. E. Ugen, V. Srikantan, M. G. Agadjanyan, K. Dang, Y. Refaeli, A. I. Sato, J. Boyer, W. V. Williams, D. B. Weiner, Gene inoculation generates immune responses against human immunodeficiency virus type 1. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 90, pp. 4156- 4160 ,(1993) , 10.1073/PNAS.90.9.4156
J. Wolff, R. Malone, P Williams, W Chong, G Acsadi, A Jani, P. Felgner, Direct gene transfer into mouse muscle in vivo. Science. ,vol. 247, pp. 1465- 1468 ,(1990) , 10.1126/SCIENCE.1690918
Gyula Acsadi, George Dickson, Donald R. Love, Agnes Jani, Frank S. Walsh, Asitha Gurusinghe, Jon A. Wolff, Kay E. Davies, Human dystrophin expression in mdx mice after intramuscular injection of dna constructs Nature. ,vol. 352, pp. 815- 818 ,(1991) , 10.1038/352815A0
NORMAN L. LETVIN, CAROL I. LORD, NORVAL W. KING, MICHAEL S. WYAND, KYL V. MYRICK, WILLIAM A. HASELTINE, Risks of handling HIV. Nature. ,vol. 349, pp. 573- 573 ,(1991) , 10.1038/349573A0
Bernard Moss, Thomas R. Fuerst, Charles Flexner, Ambros Hugin, Roles of vaccinia virus in the development of new vaccines Vaccine. ,vol. 6, pp. 161- 163 ,(1988) , 10.1016/S0264-410X(88)80021-5