Cognitive activity and cognitive decline in a biracial community population

摘要: Background: Frequent participation in cognitively stimulating activities has been associated with reduced risk of AD several prospective studies. However, the association cognitive activity decline, principal manifestation AD, is not well understood. Methods: More than 4,000 older residents a geographically defined biracial community Chicago were interviewed at approximately 3-year intervals for an average 5.3 years. Each interview included administration four function tests from which previously established global measure was derived. At baseline, each person rated frequency (e.g., reading magazine) composite Results: Cognitive scores ranged 1 to 5 (mean = 3.14, SD 0.66), higher indicating more frequent participation. decline during follow-up. In model that controlled baseline level cognition, age, sex, race, and education, 1-point increase score 19% decrease annual rate (p Conclusion: persons.