Randomized clinical trial comparing laparoscopic and open surgery for colorectal cancer within an enhanced recovery programme.

摘要: Background: Laparoscopic resection of colorectal cancer may improve short-term outcome without compromising long-term survival or disease control. Recent evidence suggests that the difference between laparoscopic and open surgery be less significant when perioperative care is optimized within an enhanced recovery programme. This study compared outcomes such a programme. Methods: Between January 2002 March 2004, 62 patients were randomized on 2 : 1 basis to receive (n = 43) 19) surgery. All entered into Length hospital stay was primary endpoint. Secondary functional recovery, quality life cost assessed for 3 months after surgery. Results: Demographics two groups similar. 32 (95 per cent confidence interval (c.i.) 7 51) shorter than (P 0·018). Combined hospital, convalescent readmission 37 c.i. 10 56) 0·012). The relative risk complications, results data similar in groups. Conclusion: Despite optimization cancer, better following There no deterioration increased associated with approach. Copyright © 2005 British Journal Surgery Society Ltd. Published by John Wiley & Sons,