Abnormal tryptophan metabolism in pregnancy and with the oral contraceptive pill. II. Relative levels of vitamin B6-vitamers in cord and maternal blood

摘要: In an investigation of the basis abnormal tryptophan metabolism during pregnancy or oral contraceptive (OC) use blood was sampled from mother-fetus pairs and analyzed for levels Vitamin B6 vitamers erythrocyte aminotransferase activity. Vitamer (in mmcg/100 ml plasma) mother cord respectively were 193 vs. 894 pyridoxine (p < .01) 309 972 pyridoxal .001) 483 636 pyridoxamine (n.s.). Enzyme activity also 50% higher in than maternal both oxalacetic .0001) pyruvic .01). The apparent ability fetus to concentrate could result depletion stores under conditions marginal intake. women on OCs increased plasma glucocorticoids can induced enzymes requiring which turn vitamin depletion. For groups would be result. To avoid metabolites it might well administer daily recommended dietary allowance pregnant OC users.