TNF-α, but not IFN-γ, regulates CCN2 (CTGF), collagen type I, and proliferation in mesangial cells: possible roles in the progression of renal fibrosis

作者: Laurinda A. Cooker , Darryl Peterson , Joann Rambow , Melisa L. Riser , Rebecca E. Riser

DOI: 10.1152/AJPRENAL.00508.2006

关键词:

摘要: Connective tissue growth factor (CCN2) is a profibrotic acting downstream and independently of TGF-β to mediate renal fibrosis. Although inflammation often involved in the initiation and/...

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