Tissue protection against oxidative stress.

摘要: We used an enhanced luminescence technique to study the response of rat tissues, such as liver, heart, muscle and blood, oxidative stress determine their antioxidant capacity. As previously found for liver homogenate, intensity light emission (E) tissue homogenates blood samples, stressed with sodium perborate, is dependent on concentration, dose-response curves can be described by equation E=a·C/exp(b·C). Theb value depends defence capability tissues. In fact, it increases when are supplemented antioxidant, correlated capacity, evaluated two set up methods both using same technique. Our results indicate that order capacity tissues liver>blood>heart>muscle. Thea systems catalysing production radical species. related level hemoproteins, which known act catalysts in from hydroperoxides. The proposed describe relation simple handle permits immediate connection characteristics analysed pro-oxidant treatment. However, best describes above all following: E=α·C/exp(β·Cδ). parameter δ assumes values smaller than 1, seem depend relative amounts hemoproteins antioxidants. extension analysis mitochondria shows they respond a way analogous adherence curve course predicted E=a·C/exp(b·C) again hemoprotein content.