Hepatitis B virus infection in children.

摘要: For two decades, hepatitis B vaccine has been integrated into national routine childhood vaccination programs in almost all countries. The prevalence of HBsAg decreased children worldwide. However, there are who miss the benefit some regions and Long-term follow-up studies have revealed clinical outcomes chronic virus infection children. A small percentage chronically infected develop liver cirrhosis hepatocellular carcinoma. it is controversial should be treated when antiviral treatment initiated Compared with adult studies, data insufficient to evaluate pathogenesis efficacy childhood. New drugs approved for adults. Also, oral administered pregnant women reduce mother-to-child transmission rate.