作者: Sven-Olof Granstam , Sara Rosengren , Ola Vedin , Tanja Kero , Jens Sörensen
DOI: 10.3109/13506129.2012.761967
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摘要: AbstractAims: To characterize patients with cardiac amyloidosis using echocardiography, electrocardiogram (ECG) and right heart catheterization (RHC).Methods results: Fourteen biopsy verified light chain or transthyretin were included. All had failure markedly elevated NT-proBNP. Echocardiography demonstrated biventricular hypertrophy, left atrial enlargement normal to slightly reduced ventricular ejection fraction. Tissue Doppler septal e´ was low median E/e´ high. Within 6 months RHC performed in eight of the patients. The restrictive filling pattern by echocardiography corresponded well pulmonary wedge pressure (21 mmHg). Systolic artery (SPAP) increased, whereas output stroke volume seen be decreased both methods. ECG demonstrated: voltage (36%), abnormal R-progression (65%), ST-T abnormalities (71%) high incidence fibrillation (36%). In addit...