High expression of carbonic anhydrase IX is significantly associated with glandular lesions in gastroesophageal junction and with tumorigenesis markers BMI1, MCM4 and MCM7
作者： Aaron R. Huber , Dongfeng Tan , Jun Sun , David Dean , Tongtong Wu
DOI: 10.1186/S12876-015-0310-6
关键词:
摘要: Background Carbonic anhydrase IX (CA9) is a transmembrane glycoprotein related to hypoxia. Increased CA9 expression has been associated with decreased survival and cancer progression targeted as potential therapy for several cancers, including esophageal cancer. The reported percentages of in adenocarcinoma vary, precancerous lesions not well studied.
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